In the European Union (EU) and United Kingdom (UK), there are an estimated 3.2 and 4.7 million people living with HCV and HBV infection, respectively1-3

Approximately two-thirds of those with HCV are unaware of their status3

Untreated, chronic HCV and HBV may lead to progressive fibrosis, cirrhosis and hepatocellular carcinoma (HCC)4-6

How can primary care providers make a difference?

Opportunistically test people with risk factors for HCV, and HBV

Confirmed HCV: In the absence of contraindications, antiviral treatment should be considered for all individuals5

Confirmed HBV: Monitor to assess for phase of disease and identify when a person should be considered for treatment7

Hepatic Health provides an overview of important issues to enable primary care providers to feel comfortable in the management of people with HCV and HBV, and to ensure that those most in need of treatment are identified and provided with the opportunity to access it.

Community based management


This page explores indications for treatment, antiviral therapy, clinical considerations and long-term patient management.

Assessment and diagnosis


From information on screening tests to advice on when to refer patients with HCV to liver specialists, this page offers a comprehensive overview of the assessment and diagnosis of HCV.

Burden of HBV


Information on the epidemiology of hepatitis B, transmission, at risk populations and natural history. 

Prevention and diagnosis


Identifying and screening patients at risk of HBV in primary care, provides a gateway to both prevention and treatment services. 

Treatment and management


Information on HBV management options, lifelong monitoring, possible antiviral therapy and surveillance for hepatocellular carcinoma (HCC).

Liver disease toolkits


Discover Hepatic Health toolkits for HCV and HBV, with resources covering prevention, testing, guidelines and more.


  1. Hofstraat SHI, et al. Current prevalence of chronic hepatitis B and C virus infection in the general population, blood donors and pregnant women in the EU/EEA: a systematic review. Epidemiol Infect 2017;11:1-13.
  2. European Centre for Disease Prevention and Control. Hepatitis B and C epidemiology in selected population groups in the EU/EEA. Stockholm: ECDC; 2018.
  3. European Union HCV Collaborators. Hepatitis C virus prevalence and level of intervention required to achieve the WHO targets for elimination in the European Union by 2030: a modelling study. Lancet Gastroenterol Hepatol 2017;2:325–336.
  4. World Health Organization. Guidelines for the care and treatment of persons diagnosed with chronic hepatitis C virus infection 2018. Available at: (accessed October 2018).
  5. EASL. EASL recommendations on treatment of hepatitis C 2018. J Hepatol 2018;69:461-511.
  6. Lavanchy D. Hepatitis B virus epidemiology, disease burden, treatment, and current and emerging prevention and control measures. J Viral Hepat 2004;11:97–107.
  7. EASL. Clinical practice guidelines on the management of hepatitis B virus infection 2017. Available at: (accessed November 2018).