Hepatitis C toolkit
Further information on the investigation and management of patients with hepatitis C virus (HCV) infection is located here. For ease of use, information is divided into topics with resources within each topic ordered by geographic application and categorised as worldwide, regional or country-specific. Please click on the links below for access to a range of links and services.
Although Gilead makes every effort to ensure the links provided are accurate, up-to-date and relevant, we cannot take responsibility for pages maintained by external providers. Gilead does not routinely screen, approve, review or endorse the contents of or use of any of the products or services that may be offered by these external sites.
Prevention
Regional
European Centre for Disease Prevention and Control
Hepatitis B and C epidemiology in selected population groups in the EU/EEA 2018
Public health guidance in brief on HIV, hepatitis B and C testing in the EU/EEA 2018
Guidance in brief: Prevention and control of blood-borne viruses in prison settings 2018
Hepatitis B and C testing activities, needs, and priorities in the EU/EEA 2017
France
French Institute for Public Health Surveillance
Hepatitis B and C: surveillance and prevention
Ministries of Social Affairs and Health
Management of people infected with HBV or HCV virus
Germany
European Commission
Policies for sexually transmitted infections
German Liver help
Hepatitis B and C tests: people at risk of infection, 2017
German guidelines for the management of viral hepatitis
Hepatitis C testing activities, needs and priorities in the EU
Hepatitis C prevention and treatment
Robert Koch Institute
Brief guide to public health on HIV, hepatitis B and C in the EU / EEA 2018
Hepatitis B and C testing: people at risk of infection, 2017
Hepatitis C epidemiology in selected populations in the EU / EEA 2018
Thieme Journal
Brief Guide: Prevention and Control of Bloodborne Viruses (HCV) in Prisons 2018
World Health Organization
Guidelines for the prevention, care and treatment of persons with chronic hepatitis B and C infection, 2015
Italy
Spain
Government of Spain, Ministry of Health, Consuption and Social Welfare
HepC strategic plan
Strategic plan report for HCV treatment
Strategic plan for the Hepatitis C approach in the health national
Strategic plan for chronic HCV approach
Strategic plan for tackling Hepatitis C in the Spanish national health system
Spanish association for the study of the liver
Advances towards the elimination of Hepatitis C in Spain
AEEH Position paper on the elimination of Hepatitis C in Spain
UK
Scottish Parliament Health and Sport Committee
Preventative Action and Public Health 2018
Screening and diagnosis
Worldwide
World Health Organization
Guidelines for the screening, care and treatment of persons with chronic hepatitis C infection, 2016
Regional
European Association for Study of the Liver (EASL)
EASL Recommendations on Treatment of Hepatitis C, 2018
HCVGuidelines.org
Guidelines developed by the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA).
HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C, 2018
HCV in Europe
National HCV testing guidelines for countries within the European Economic Community (EEC), 2004-2017
France
French Institute for Public Health Surveillance
Fact sheet Place of Point-of-Care Tests (POCTs) in hepatitis C screening strategy
Screening algorithms for HBV and HCV
French National Agency for Accreditation and Evaluation in Health
HBV and HCV Biological screening strategies
Hepatitis B and C diagnosing algorithms
Hepatitis C screening
Update of laboratory medicine procedures related to the diagnosis and management of hepatitis B, C and D
Ministries of Social Affairs and Health
Management of people infected with hepatitis B or C
Germany
German liver and hepatitis support groups
German publications that can be downloaded for free
Italy
Evidence – open access journal
HCV and new drugs: no to population screening, yes to prevention measures
Italian Ministry of Health
Hepatitis C- Diagnosis
Spain
Catalan Hepatic Diseases Association
Basic information on Hepatitis C: Diagnosis of hepatitis C: how to know if you have the disease. HCV tests. Screening.
Spanish association for the study of the liver
HCV one step diagnosis
Recommendations consensus for the early diagnosis, prevention and clinical care of hepatitis C in Primary Care
UK
BVHG/BASL/BSG/BHIVA/BIA/CVN
Guidelines for management of chronic HCV infection, 2017
National Institute for Health and Care Excellence (NICE)
Hepatitis B and C testing: people at risk of infection, 2013
Baseline assessment tool, 2012
Treatment guidelines
Worldwide
International Union Against Sexually Transmitted Infections (IUSTI)
European Guideline for the screening, prevention and initial management of hepatitis B & C infections in sexual health settings, 2017
World Health Organization
Guidelines for the screening, care and treatment of persons with chronic hepatitis C infection, 2016
Regional
European Association for Study of the Liver (EASL)
EASL Recommendations on Treatment of Hepatitis C, 2018
European Centre for Disease Prevention and Control
Public health guidance on HIV, hepatitis B and C testing in the EU/EEA, 2018
HCVGuidelines.org (AASLD and IDSA)
Guidelines developed by the American Association for the Study of Liver Diseases (AASLD) and the Infectious Diseases Society of America (IDSA).
HCV Guidance: Recommendations for Testing, Managing, and Treating Hepatitis C, 2018
France
French Institute for Public Health Surveillance
AFEF position paper on HAART (Peg-INF + ribavirin + protease inhibitor)
Consensus conference – Hepatitis C treatment
Direct-acting antivirals (DAA) HCV management
Viral hepatitis C treatment – Expert advice 2015
French National Agency for Accreditation and Evaluation in Health
Acts and benefits – long term condition – chronic hepatitis C
Doctor’s guide to Hepatitis C
Ministries of Social Affairs and Health
Management of people infected with hepatitis B or C
Germany
Apps for liver diagnostics
The iLiver app is an EASL-reviewed bedside resource that provides up-to-date clinical recommendations and information on more than 26 different liver diseases.
Fibro Scan enables non-invasive liver diagnosis and treatment for patients with hepatitis B and C
Global Hepatitis Report 2017
Deutsche Liver Foundation
Interactions with HEP drugs
Note: The Hep iChart (Liverpool Drug Interactions Group) app can be downloaded from iTunes or the Google Play Store. Public Health Deutschland
Health care professionals
The Green Book
World Health Organization, Europe
Information on hepatitis in the WHO European Region
Italy
International health
Access to Hepatitis C treatement. The solution.
Italian association for the study of the liver
HCV hepatitis: new criteria for access to care
Practical indications for a shared management model between general practioner and hepatologist of the patient with chronic hepatitis B and hepatitis C virus.
Regional health and social agency
Chronic hepatitis C treatment in adults
Spain
Spanish association for the study of the liver
AEEH HCV virus treatment guide
AEEH/SEIMC (Spanish association for the study of the liver / Spanish society of infectious diseases and clinical microbiology) HCV management guidelines
Recommendations consensus for the early diagnosis, preventions and clinical care of hepatitis C in Primary Care
Summary-table of indications
UK
British Association for Sexual Health and HIV
2017 interim update of the 2015 BASHH National Guidelines for the Management of the Viral Hepatitides
BVHG/BASL/BSG/BHIVA/BIA/CVN
Guidelines for management of chronic HCV infection, 2017
National Services Scotland
National Clinical Guidelines for the treatment of HCV in adults, 2018
Public Health England
Hepatitis C: guidance, data and analysis, 2018
Elimination information
Worldwide
Duffy Health Center shared medical appointments – Massachusetts, USA
A shared medical appointment model for vulnerable patients provided by non-specialist providers.
HCV care in a low threshold setting in Oslo – Norway
A primary care, low-threshold HCV clinic with a network-based, flexible, ambulant model of care.
Kombi Clinic outreach model of GP care – Brisbane, Australia
A GP-led, mobile hepatitis clinic engaging with disenfranchised, disempowered and socially isolated populations.
ARISTOTLE HCV-HIV project: peer support – Athens, Greece
A community-based, peer-driven referral process to increase linkage to care and treatment among PWID.
Cool Aid Community Health Centre nurse-led model of HCV care – British Columbia, Canada
A nurse-led ‘seek and treat’ approach to identify high-risk patients in supportive housing centres.
France
SAFE remote HCV screening project
Increasing linkage to care for PWUD using remote methods of education and screening.
Toulouse mobile liver disease team
A service offering onsite screening for HCV, liver disease assessment, pre-treatment counselling and follow-up.
Germany
From HCV testing to treatment in social relief centres in Amsterdam
HCV screening and linkage to care in social relief shelters and walk-in centres across Amsterdam.
Italy
Caserta model of integrated HCV care
A simplified care pathway between hospitals, addiction units and prisons in a high prevalence area.
Villa Maraini Foundation integrated HCV care
Collaboration between a low-threshold service and tertiary institution to facilitate linkage to care for hard-to-reach HCV patients.
Regional HCV elimination plan in Veneto
A test and treat ‘point of care’ HCV strategy among addiction services and prisons.
Spain
The Catalan model of hepatitis care, a special approach in prisons
An initiative to introduce systematic screening for HCV for all individuals admitted to prison.
Andalusia one-step diagnosis
Reflex testing for HCV has been incorporated into all microbiology laboratories in Andalusia, Spain.
Holistic HCV elimination in Tenerife
A local initiative with the collaboration of multiple stakeholders to improve linkage to care in Tenerife, Spain.
The Catalan model of hepatitis care
Broad multi-stakeholder engagement, with the aim of eliminating HCV as a public health threat.
Information for patients with HCV
Regional
The European Hepatitis C Initiative
ELPA (European Liver Patients’ Association)
The Association was formed in 2004 by the amalgamation of 13 patient groups from 10 European and Mediterranean Basin countries
France
French Institute for Public Health Surveillance
Management of your chronic HCV condition – understand how to improve your health living with a chronic hepatitis C
French National Agency for Accreditation and Evaluation in Health
Guide – long term condition – Management of your condition, chronic hepatitis C – to live with a chronic hepatitis C
Ministries of Social Affairs and Health
Management of people infected with hepatitis B or C
Management of treatment and follow-up of people infected with HCV virus
SOS Hepatitis Federation: Hepatitis and Liver diseases
To live with a hepatitis
Germany
German liver and hepatitis support groups
German publications that can be downloaded for free
Italy
HepC Onlus association
EpaC – the portal to patients with hepatitis and liver disease – Epatite C
Italian Ministry of Health
Epatite C – Ministero della Salute/ Hepatitis C – Ministry of Health
Viral hepatitis – Hepatitis B (EPICENTRO: the public health epidemiology portal)
Viral hepatitis – Hepatitis C (EPICENTRO: the public health epidemiology portal)
Spain
Catalan Hepatic Diseases Association
To live with Hepatitis C – Selfcare and quality of life
Chronic HCV Extrahepatic manifestations
Common symptoms and their management
Complementary therapies
Diet and nutrition
Introduction
Relevant parameters in the analysis of a person with Hepatitis C
To reveal or not that you live with Hepatitis C
Hepatitis C treatment
Aspects to consider in order to optimize the quality of life during the treatment
Available drugs for the treatment of Hepatitis C
Hepatitis C Treatment adherence and how to optimize it
Possible results in HCV virus treatment
Treatment objective
UK
British Liver Trust
The British Liver Trust provides a range of publications that can be downloaded for free.
Key publications have also been translated for several different nationalities:
Helpline: 0800 652 7330
UK Liver and Hepatitis Support Groups
Public Health England
Hepatitis C: information for patients
The Hepatitis C Trust
The Hepatitis C Trust is the national UK charity for hepatitis C. It is a patient-led and patient-run organisation.
NHS
General patient information on hepatitis C
Resources for healthcare professionals
Worldwide
World Health Organization
Hepatitis C fact sheet
Global hepatitis report 2017
World Health Organization, Europe
Information on hepatitis in the WHO European region
Regional
European Association for the Study of the Liver (EASL)
EASL HCV Advisor
The HCV Advisor app is a tool provided free by EASL to those treating patients with HCV. Patient information is entered into the app and users are provided with treatment options based on the EASL Recommendations for Treatment of Hepatitis C.
ILIVER
iLiver app is EASL’s own reviewed bedside resource that provides up to date clinical recommendations and information in more than 26 different areas of liver disease.
HEPscreen
Screening for hepatitis B and C among migrants in the European Union
France
French Institute for Public Health Surveillance
Doctor’s guide to hepatitis C
Ministries of Social Affairs and Health
Management of people infected with hepatitis B or C
Management of treatment and follow-up of people infected with HCV virus
SOS Hepatitis Federation: Hepatitis and Liver diseases
Hepatitis transmission modes
Germany
Apps for liver diagnostics
The iLiver app is an EASL-reviewed bedside resource that provides up-to-date clinical recommendations and information on more than 26 different liver diseases.
Fibro Scan enables non-invasive liver diagnosis and treatment for patients with hepatitis B and C
German Liver Foundation
Interactions with HEP drugs
Note: The Hep iChart (Liverpool Drug Interactions Group) app can be downloaded from iTunes or the Google Play Store. Public Health Deutschland
Health care professionals
The Green Book
Robert Koch Institute
Globaler Hepatitis-Bericht 2017/ Global Hepatitis Report 2017
World Health Organization, Europe
Information on hepatitis in the WHO European Region
Italy
Italian Ministry of Health
National plan for viral hepatitis B and C prevention
Loredano Giorni – Interview
The new drugs for the treatment of Hepatitis C: challenges
Viral hepatitis – Hepatitis B (EPICENTRO: the public health epidemiology portal)
Viral hepatitis – epidemiology
Spain
American Association for the Study of Liver Diseases
Hepatitis C Guidance: AASLD-IDSA recommendations for testing, managing, and treating adults infected with Hepatitis C virus
Spanish association for the study of the liver
Hepatology White Book Spain
UK
British Liver Trust
Love your liver national awareness campaign
HCV Action
A network of healthcare professionals from across the UK that provide resources for commissioners, and medical and drug services professionals, promoting good practice in HCV care.
NHS England
Clinical Commissioning Policy Statement: Treatment of chronic Hepatitis C in patients with cirrhosis
Public Health England
Hepatitis C: information for GPs
University of Liverpool
HEP Drug Interactions
Calculators and screening tools
International
AUDIT Alcohol Consumption Questions (AUDIT-C)
AST to Platelet Ratio Index (APRI) Calculator
CAGE Questionnaire for Detecting Alcoholism
Child-Pugh Score for Cirrhosis Mortality
Creatinine Clearance (CrCl) Calculator
Fibrosis-4 (FIB-4) Calculator
MELD Score (Model for End-Stage Liver Disease)
France
Body Mass Index (BMI)
Child Pugh Score
Cirrhosis scale
Fibrosis-4 (FIB-4) Score
Glasgow or Osborne Score
MELD (Model for End Stage Liver Disease) Score
NAFLD Score
Score APRI
Germany
AST to Platelet Ratio Index (APRI) Calculator
AUDIT Alcohol Consumption Questions (AUDIT-C)
BMI Healthy Weight Calculator (NHS)
CAGE Questionnaire for Detecting Alcoholism
Child-Pugh Score for Cirrhosis Mortality
Creatinine Clearance (CrCl) Calculator
eGFR Calculator (The Renal Association)
Fibrosis-4 (FIB-4) Calculator
MELD Score (Model for End-Stage Liver Disease)
Italy
Audit alcohol questions
APRI Calculator
BMI Calculator
CAGE Questionnaire for detecting alcoholism
Creatinine Clearance
eGFR calculator
Fibrosis-4 (FIB-4) Calculator
MELD Score (Model for End-Stage Liver Disease)
Spain
Are you an active person?
AST to Platelet Ratio Index (APRI) Calculator
AUDIT Alcohol Consumption Questions (AUDIT-C)
Autoimmune hepatitis score calculator
BMI Calculator
Child-Pugh Score
Fatty Liver Index Calculator
Fibrosis-4 (FIB-4) calculator
Glasgow alcoholic hepatitis score
Insulin resistance índex calculator
Know your consumption
Maddrey score calculator
Model for End Stage Liver Disease Score
NAFLD calculator
NAFLD Calculators (includes APRI índex, NAFLD fibrosis score, Fibrosis 4 score, AST/ALT)
Viral Hepatitis Risk Asessment
UK
Continuing medical education
Regional
Clinical Care Options
Medical education materials, conference coverage and opinion pieces dealing with the management of viral hepatitis
European Association for the Study of the Liver (EASL)
The EASL LIVERTREETM
EASL members have access to the LiverTree, an online medical educational resource designed by hepatologists for hepatologists.
LiverLearning®
LiverLearning® is the official eLearning portal of AASLD. Users can access educational resources by categories, content type, and events — including videos and slide decks.
European Centre for Disease Prevention and Control
Training on infection control in the EU/EEA
France
Ministries of Social Affairs and Health
Management of people infected with hepatitis B or C
Germany
Clinical care options
Medical training materials, conference reports and opinion papers dealing with the management of viral hepatitis
European Center for Disease Prevention and Control
Anti-infection training in the EU / EEA
Learning to live in Berlin
Life Learning Berlin gives users access to educational resources by category, content type, and event – including videos and slide decks
Online advice on substance abuse and health
Online advice on substance abuse and associated health
The EASL LIVERTREETM
EASL members have access to the LiverTree, an online educational resource for medical purposes developed by hepatologists for hepatologists.
Italy
Italian association for the study of the liver
Italian association for the study of the liver
Hepatitis information
Italian foundation for hepatology research
Spain
Elsevier
Multidisciplinary hepatitis C management Online training
e-learning SEPD: Sociedad Espanola de Patología Digestiva
Global benefits of Hepatitis C antiviral treatment
Spanish association for the study of the liver
Hepatology White Book Spain
UK
Royal College of General Practitioners (RCGP)
RCGP Hepatitis C: Enhancing Prevention, Testing and Care course.
RCGP Substance Misuse and Associated Health (SMAH) alcohol certificate course.
HEP-C Community Summit
This is an annual conference that brings together people from the affected communities, advocates, researchers, healthcare providers, harm reduction practitioners, and policymakers to discuss and to develop an enduring cooperation for building the road to HCV elimination.
National and international policies
Worldwide
Regional
ACHIEVE (Associations Collaborating on Hepatitis to Immunize and Eliminate the Viruses in Europe)
A collaborative of organisations including: the European Liver Patients’ Association (ELPS); EASL International Liver Foundation, World Hepatitis Alliance; Hepatitis B and C Policy Association; European Aids Treatment Group (EATG); Correlation Network; Viral Hepatitis Prevention Board and ISGlobal, University of Barcelona.
Hepatitis C Elimination in Europe, 2017
Hepatitis B & C Public Policy Association
A not-for-profit association responsible for the annual hepatitis B and C summit conference in Europe
France
French Institute for Public Health Surveillance
AFEF recommendations for the elimination of hepatitis C virus infection in France
AFEF recommendations on the management of viral hepatitis C
French National Agency for Accreditation and Evaluation in Health
Fact sheet Place of Point-of-Care Tests (POCTs) in hepatitis C screening strategy
To improve hepatitis B and C screening
Germany
German Society of Gastroenterology, Digestive and Metabolic Diseases
Hepatitis C DGVS guidelines
Hepatitis B & C Association
A non-profit association hepatitis B and C in Germany
Cooperation in hepatitis to immunize and eliminate viruses in Europe
Ministry of Health
Combating hepatitis B and C by the year 2030
Public Health Germany
Acute Hepatitis C (Germany): Annual Report 2017Akute Hepatitis C (Deutschland): Jahresbericht 2018
Robert Koch Institute (RKI)
Hepatitis B and C: Local surveillance standards
Italy
Spain
Alliance for the elimination of viral hepatitis in Spain
Alliance for the elimination of viral hepatitis in Spain
Catalan Hepatic Diseases Association
Road to elimination: barriers and best practices in the management of hepatitis C. Overview of HCV care in Europe and Australia
UK
All-Party Parliamentary Group on Liver Health Inquiry Report
Eliminating Hepatitis C in England, 2018
Public Health England
Hepatitis B and C: local surveillance standards
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IHQ/LVD/2020-05//0020 Date of preparation: May 2020